Updated PREDICT tool for breast cancer prognostication outperforms existing model

Updated PREDICT tool for breast cancer prognostication outperforms existing model

The PREDICT prognostication and treatment tool was developed in 2010 to help guide decisions for patients with invasive early-stage breast cancer. However, many improvements have occurred since the model’s development, which were not incorporated to reflect more contemporary treatment options. In particular, the benefits or harms associated with radiotherapy were lacking. Now, leading researchers have published an updated version of the PREDICT model in the Nature-partner journal Breast Cancer. The model was refined using a UK national data set of over 35,000 patients diagnosed from 2000 to 2017. The beneficial effect of radiotherapy on breast cancer mortality and the harmful effect of both chemotherapy and radiotherapy on other causes of mortality were included. In summary, the latest PREDICT model outperformed the existing model and will be implemented in the online tool to provide more accurate treatment benefit predictions in the future.

READ THE ARTICLE – https://www.nature.com/articles/s41523-024-00612-y

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