Plant-derived SVC112 hits cancer stem cells, leaves healthy cells alone
The red, tube-shaped flowers of the firecracker bush (Bouvardia ternifolia), native to Mexico and the American Southwest, attract hummingbirds. The […]
Read MoreThe red, tube-shaped flowers of the firecracker bush (Bouvardia ternifolia), native to Mexico and the American Southwest, attract hummingbirds. The […]
Read MoreIn a new qualitative study, a team of scientists at Dartmouth and Dartmouth-Hitchcock’s Norris Cotton Cancer Center and the Breast Cancer Surveillance Consortium led by Karen Schifferdecker, PhD, MPH, and Anna Tosteson, ScD, sought to explore women’s knowledge and perceptions of breast density and experiences of breast cancer screening across three states with and without notification laws.
Read MoreImmune checkpoint inhibitors are important medications that boost the immune system’s response against certain cancers; however, they tend to be ineffective against glioblastoma, the most deadly primary brain tumour in adults. New research in mice led by investigators at Massachusetts General Hospital (MGH) and the University of Florida reveals a promising strategy that makes glioblastoma susceptible to these medications.
Read MoreA comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types.
Read MoreArtificial intelligence (AI) technology developed by the RIKEN Center for Advanced Intelligence Project (AIP) in Japan has successfully found features in pathology images from human cancer patients, without annotation, that could be understood by human doctors.
Read MoreA fundamental change in our understanding of the childhood kidney cancer Wilms’ tumour is on the horizon, after the discovery of its earliest genetic root by scientists at the Wellcome Sanger Institute and their collaborators.
Read MorePhysicians who treat patients with triple negative breast cancer have two new ways to predict which patients may benefit most from the well-established post-surgery treatment known as AC chemotherapy, short for adjuvant doxorubicin and cyclophosphamide.
Read MoreMining the rich uncharted territory of the genome or genetic material of a cancer cell has yielded gold for Princess Margaret scientists: new protein targets for drug development against prostate cancer.
Read MoreA new screening system developed by scientists at the UCLA Jonsson Comprehensive Cancer Center leverages redundancy in an important component of a cell – nucleotide metabolism – to help identify new drugs that specifically and potently block processes that are essential for cancer cell growth.
Read MoreCancer therapies can affect the whole cardiovascular system, but these cardiotoxic effects are generally reported as changes in left ventricular (LV) ejection fraction. The most common cardiovascular adverse effects are LV dysfunction and heart failure (HF). Other adverse effects include hypertension, acute coronary syndromes, thromboembolic events, rhythm disturbances, and valvular and/or pericardial disease. Hence, prediction, early recognition, and timely management of cardiovascular complications in patients with cancer are gaining importance. This need gave birth to the concept of interdisciplinary cardiology-oncology (cardio-oncology) care delivered through teams of cardiologists, oncologists, and hematologists.
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